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Nature Reviews Drug Discovery: This Review profiles established and emerging glucagon-like peptide (GLP-1) based medicines, focusing on novel GLP-1 receptor agonists and GLP-1-based multi agonists, and discusses considerations, challenges and future
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GLP-1 receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials have shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal. Read
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